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Thomas Duff may refer to:
Thomas Duff (architect) (1792–1848), Irish architect
Thomas Duff (businessman) (born 1956), American businessman
Thomas Duff (politician) (1870–1949), Australian politician
Thomas J. Duff, American architect
Thomas Neil Duff (1896–1978), politician in Ontario, Canada
Tom Duff (born 1952), Canadian computer programmer
Tommy Duff (1905–1951), English footballer
General info from Wikipedia.org