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Ghirlandaio (pronounced [ɡirlanˈdaːjo]) is the surname of a family of Renaissance Italian painters:
Domenico Ghirlandaio (1449–1494), painter of fresco cycles and Michelangelo's teacher
Davide Ghirlandaio (1452–1525), younger brother of Domenico
Benedetto Ghirlandaio (1458–1497), younger brother of Domenico and Davide
Ridolfo Ghirlandaio (1483–1561), son of Domenico
General info from Wikipedia.org