According to the Hebrew Bible, the Tribe of Manasseh (; Hebrew: שֵׁבֶט מְנַשֶּׁה‎‎ Ševet Mənašše, Tiberian: Šēḇeṭ Mănašše) was one of the twelve tribes of Israel. After the Assyrian invasion of 720 BCE, it is counted as one of the ten lost tribes. Together with the Tribe of Ephraim, Manasseh also formed the House of Joseph.
Academic consensus, informed by historical context, textual analysis, and archaeological evidence, largely views the Israelite tribes as eponymous figures representing social or regional groups formed from indigenous Canaanite populations during the Late Bronze and Early Iron periods, rather than as actual historical individuals.