"Alexamenos Graffito"
The Alexamenos graffito (a.k.a. graffito blasfemo) is a piece of Roman graffito scratched in plaster on the wall of a room near the Palatine Hill in Rome, Italy, which has now been moved to the Palatine Museum.
It may be meant to depict Jesus, and if so, is one of the earliest known pictorial representation of the Crucifixion of Jesus. While it is hard to date, it is estimated to have been made around the year 200 AD.
The image appears to show a young man worshipping a crucified, donkey-headed figure. The Greek inscription roughly translates to "Alexamenos worships [his] god," suggesting that the graffito was meant to mock a Christian named Alexamenos.