Jerome devoted much of his life to biblical scholarship, translation, teaching, and the defense of Christian asceticism. He believed that knowledge of Scripture should reshape conduct, drawing believers toward prayer, chastity, generosity, and disciplined service. His correspondence reveals a learned and sometimes combative teacher who regarded careful study as a religious duty.
He strongly promoted virginity and monastic life, especially in writings addressed to Christian women and their families. His praise of celibacy sometimes employed comparisons with marriage that provoked criticism. Jerome also defended the goodness of creation and the body against teachings that treated material existence as inherently evil.
His central achievement was not a new systematic theology but the effort to make the biblical text more accurately available to Latin-speaking Christians.