Psalm 22:22 marks a dramatic turn from suffering to praise. The speaker declares that he will proclaim God's name to his brothers and praise Him in the midst of the congregation. The movement implies that the sufferer who appeared abandoned and near death has been heard and vindicated by God.

John 20:17 records the risen Jesus telling Mary Magdalene to go to "my brothers" and announce His return to the Father. Hebrews 2:12 makes the connection even more explicit by quoting Psalm 22:22 as words of Christ: "I will tell of your name to my brothers." Thus the psalm's transition from suffering to proclamation among the brethren fits the resurrection and vindication of Jesus. The New Testament itself places Psalm 22:22 on the lips of Christ, making this a particularly strong messianic application.