Isaiah 40 announces comfort and the coming of the LORD, beginning with the voice preparing His way and continuing with images of divine power, reward, and shepherd-like care.
The fulfillment passages listed here (Rev 22:12) illuminate the Christian application summarized as "He will come to reward." The correspondence is meaningful within the New Testament portrait of Jesus, but where the New Testament does not explicitly quote this exact Isaiah verse as fulfilled, it is best described as a theological or messianic correspondence rather than claiming more precision than the biblical writers themselves state.