Genesis 49:10 contains the difficult expression traditionally translated "until Shiloh comes." The precise meaning of the Hebrew has been debated, and translations variously understand it as a personal name, "the one to whom it belongs," or a similar reference to the rightful ruler. For that reason, it is wise not to base the messianic connection solely upon the English name "Shiloh." The larger verse, however, clearly anticipates a significant ruler arising from Judah.

John 17:3 emphasizes that Jesus was sent by the Father, a major theme throughout John's Gospel. Christian interpreters have therefore associated the coming ruler of Genesis 49 with Christ, the One sent by God and belonging to Judah's line. The strongest connection is not an etymological claim that "Shiloh" simply means "One Sent," but the broader convergence of the passages: Genesis anticipates Judah's rightful ruler, and the New Testament presents Jesus as the divinely sent Messiah from that tribe.