Genesis 11:31 records Terah leaving Ur of the Chaldeans with Abraham, Sarah, and Lot intending to travel to Canaan. The family reached Harran and settled there.
Genesis 12 begins with God calling Abraham to leave his country and kindred. Abraham departed Harran at the age of seventy-five and traveled toward Canaan.
Harran and the surrounding region remained connected with Abraham's extended family. Abraham's servant later traveled toward Mesopotamia to find a wife for Isaac, and Jacob fled to the household of Laban in the same broader region.
Harran reappears in 2 Kings and Isaiah as a city conquered by the Assyrians and cited in Assyrian boasts against Jerusalem.