The Old Testament associates Galilee particularly with the northern tribal territories. Isaiah 9:1 speaks of the land of Zebulun and Naphtali and "Galilee of the nations," a passage quoted in Matthew 4 in connection with the beginning of Jesus' Galilean ministry.
Jesus grew up at Nazareth in Galilee and made Capernaum a major base for His ministry. He taught in Galilean synagogues and villages, called disciples from the region, performed numerous miracles, and repeatedly crossed or traveled around the Sea of Galilee.
After the resurrection, Matthew 28 records Jesus meeting His disciples on a mountain in Galilee and commissioning them to make disciples of all nations.