Genesis 10:11-12 includes Calah within the description of the earliest cities of Assyria following the Table of Nations. It appears together with Nineveh, Rehoboth-Ir, and Resen.
Although Calah receives little additional direct attention by name in Scripture, its later importance as an Assyrian capital connects it closely with the empire that profoundly affected Israel and Judah.
From Calah and other Assyrian royal centers, kings administered the expanding imperial system whose western campaigns eventually resulted in the conquest of the northern kingdom of Israel and invasions of Judah.