Matthew identifies Bethlehem as a town of Judea and describes Herod ruling the region at the time of Jesus' birth. John the Baptist later preached in the wilderness of Judea and baptized people who came from Jerusalem and the surrounding country.
The Gospels distinguish Judea from Galilee while describing Jesus traveling between these regions. Jerusalem and the Temple made Judea the center of Jewish religious life.
Acts 1:8 gives Judea an important place in the geographical expansion of the Christian mission: the disciples were to be witnesses in Jerusalem, throughout Judea and Samaria, and ultimately to the ends of the earth.
Acts subsequently records Christian communities spreading beyond Jerusalem into the surrounding Judean region.