Isaiah identifies himself as the son of Amoz and places his prophetic ministry during the reigns of
Uzziah,
Jotham,
Ahaz, and
Hezekiah, kings of Judah. His ministry therefore unfolded during the eighth century BC, when the Neo-Assyrian Empire posed an increasing threat to Israel and Judah.
Isaiah's call is described in Isaiah 6. In a vision he saw the Lord enthroned in holiness while seraphim proclaimed God's glory. Confronted with his own uncleanness, Isaiah was cleansed and responded to God's call with the words, "Here am I; send me."
During the Syro-Ephraimite crisis, Isaiah urged King Ahaz to trust the Lord rather than fear the coalition threatening Jerusalem. Ahaz refused the offered sign, and Isaiah announced the sign of Immanuel. Later, Isaiah strongly opposed reliance upon Egypt and other political strategies as substitutes for faith in God.
Isaiah was also active during Hezekiah's reign. When the Assyrian king Sennacherib invaded Judah and threatened Jerusalem, Isaiah assured Hezekiah that the city would not fall to the Assyrians. The biblical account records the dramatic destruction of the Assyrian force and Sennacherib's withdrawal.
Isaiah's message combines warnings of judgment with sweeping promises of hope. He speaks of a child and king associated with
David's throne, a peaceful kingdom, a remnant preserved by God, comfort after judgment, the Lord's servant, and the future glory of Zion. Later Jewish and Christian tradition contains accounts of Isaiah's martyrdom, but Scripture itself does not describe his death.