"The Virgin and Child with St. Anne and St. John the Baptist"

The piece is very large in size, consisting of eight papers glued together. Also known as the Burlington House Cartoon, it is presumed to be a sketch in planning for a painting, although the painting either no longer exists, or was never created. Leonardo often used a "cartoon" such as this as a stencil which he placed on the intended painting surface. Once fixed in place, a pin would be used to create an outline that would then guide the artist's brush. Because this piece is impeccably preserved, it is assumed that it was never put to use for this purpose. 

The drawing is notable in that it reflects Leonardo's search for perfection, even in planning for a painting. His acuity with anatomy is present in the realistic ways the figures' bodies are shown in various gestures of interaction with each other. Genuine tenderness is conveyed in the faces of the women and St. John as they reflect upon the focal point of Christ. The attention to detail for what was a preparatory drawing, underlines the artist's painstaking approach to producing art.